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"It will take a couple days to get the exact accounting of the amount donated. Then Imminst will cut a check to [the SENS Foundation, who will be managing the actual research project]. Nason [Schooler] has already begun preparations for full blown experiments and expects to keep us up to date when things start in earnest. So things are already set-up and should get going in about a week or two."
TRENDS IN MINIATURIZATION OF FUNCTIONAL ORGAN REPLACEMENTS (August 21 2009) -in-miniaturization-of-functional-organ-replacements/A dialysis machine, intended to replace the function of damaged kidneys, might weigh 55kg. Researchers now have that down to 5kg in a wearable form, a machine which does a better job to boot. Looking ahead, we'd expect even more effective implants or bracelets worn over surface veins in the 2020s - essentially viable artificial replacements for the function of an organ. This is an important trend to watch, as I believe it will ultimately contribute to enhanced longevity just as greatly as regenerative medicine: "Our vision of a technological breakthrough has materialized in the form of a Wearable Artificial Kidney, which provides continuous dialysis 24 hours a day, seven days a week ... The device - essentially a miniaturized dialysis machine, worn as a belt - weighs about 10 pounds and is powered by two nine-volt batteries. Because patients don't need to be hooked up to a full-size dialysis machine, they are free to walk, work, or sleep while undergoing continuous, gentle dialysis that more closely approximates normal kidney function. ... We believe that the Wearable Artificial Kidney will not only reduce the mortality and misery of dialysis patients, but will also result in significant reduction in the cost of providing viable health care."
GROWING NEW CORONARY ARTERIES (August 18 2009) -new-coronary-arteries/Scientists continue to experiment successfully with the use of stem cells to engineer regeneration: "researchers have identified stem cells that are able to grow new coronary arteries, a finding that could lead to new ways to treat atherosclerosis. ... We have defined this novel class of primitive cells and named them coronary vascular progenitor cells [CVPCs]. These cells possess all of the fundamental properties of stem cells and are distributed within niches located in the vessel wall of the entire human coronary circulation system. ... To test the activity of these cells, the scientists created a blockage in a coronary artery in dogs and injected human CVPCs in the blocked artery. After one month, the dogs showed improvements in blood flow and heart functioning. The researchers found that the dogs had grown large, intermediate and small human coronary arteries. ... The findings suggest that the human heart contains a reservoir of CVPCs that can be used to create a biological bypass in patients with chronic coronary artery disease and ischemic cardiomyopathy, which results when arteries that supply blood and oxygen to the heart are blocked."
A VIEW OF LONGEVITY SCIENCE FROM THE MAINSTREAM (August 18 2009) -view-of-longevity-science-from-the-mainstream/To the man in the street and mainstream journalism, medical science is nothing more than drug development - an unfortunate and blinkered viewpoint. Here is that viewpoint turned to regard research into metabolic manipulation to slow aging: "It may be the ultimate free lunch - how to reap all the advantages of a calorically restricted diet, including freedom from disease and an extended healthy life span, without eating one fewer calorie. Just take a drug that tricks the body into thinking it's on such a diet. It sounds too good to be true, and maybe it is. Yet such drugs are now in clinical trials. Even if they should fail, as most candidate drugs do, their development represents a new optimism among research biologists that aging is not immutable, that the body has resources that can be mobilized into resisting disease and averting the adversities of old age. This optimism, however, is not fully shared. Evolutionary biologists, the experts on the theory of aging, have strong reasons to suppose that human life span cannot be altered in any quick and easy way. But they have been confounded by experiments with small laboratory animals, like roundworms, fruit flies and mice. In all these species, the change of single genes has brought noticeable increases in life span."
Part One, "General Perspectives on Media and Information Literacy in the MENA Region" has four chapters. The first, introductory, chapter by Magda Abu-Fadil successfully meets its goal to "shed light on different national, local, and individual efforts to create more awareness, show the existing shortcomings, and expand the circle of stakeholders involved in MIL" (p. 14). Chapter 2, "Preliminary Comparative Analysis of Media and Information Literacy in the MENA Region," (Alton Grizzle) offers a critical comparative analysis. The author summarizes the chapter by stating:
RETRO GOAL is a fast and exciting mix of arcade Soccer action and simple team management, from the developers of hit sports games NEW STAR SOCCER and RETRO BOWL. Play the first 10 matches for free before unlocking the rest of the game to shoot for glory!With graphics inspired by the most beloved football games of 16-bit era and the accuracy of modern touchscreen controls, you'll be slotting away goal after goal with pixel-perfect precision. Choose a team from the world's favourite leagues and recruit the superstars, professionals and hotheads who will lead you to victory - then take full control on the pitch and make every touch count!
Tri, tri, tri again.Triangulate is a tactical tile game where two opponents place triangle-shaped tiles to out score one another.Every turn each player scores points by placing a triangular tile anywhere on the grid to match one of three colours and shapes.Players balance optimal scoring and tactical tile placement - what might seem a good scoring tile now could be bad later if it allows your opponent better scoring potential.The game ends when the board is full and a winner is usually declared (a draw is possible if both players are evenly matched).Triangulate features full controller support as well as on-demand colour changes with colour-blind palettes already present (plus some regular garish colour palettes).
Evil has been vanquished. Peace has returned to Ancardia, and the peasants dare to dream once more of prosperity. Seven very different factions vie for control over the cataclysmic aftermath left behind by Andor Drakon's defeat. And somewhere, deep down in an inhospitable cave, ChAoS is stirring again.Pick up your blade, prepare your spells, check your daggers and ready your bow, for you are about to enter the ominous Caverns of Chaos. Choose your allegiance carefully, for you are nothing more than an expendable asset to the masters you choose.Fight for a mercenary's glory and purse, for the justice of a folk in decline, for the light of purity or even for ChAoS itself.
Your day started as planned. Motivated and full of ambition you started the run of your life, in the middle of the desert, surrounded by like-minded people. The months of hard training should finally bear fruit. Suddenly, you were caught in a monstrous sandstorm and now you find yourself alone in an inhospitable, hot environment. Deserted and merciless, an ocean of sand stretches to the horizon.You feel the scorching heat on your skin, sand blowing right at your face, far and wide only vast desert ... but wait, what is that? Something is moving in the far distance. What happened?Starsand is a mystic survival game set among the dunes of an arcane desert. An open-world full of danger, vast environments and mysterious happenings await you! Explore, hunt, craft, build and SURVIVE.
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Dougald Anson was big even for a Terrestrial; his tawny head rode at full two meters and his wide shoulders strained the chain mail he wore. He was young, but his face had had the youth burned out of it by strange suns and wild winds around the world, was lean and brown and marked with an old scar across the forehead. His eyes were almost intolerably bright and direct in their blue stare, the eyes of a bird of prey.
Janazik was something of a dandy, and even now he wore the baggy silk-like trousers, long red sash, and elaborately embroidered blouse and vest of a Krakenaui noble. It was woefully muddy, but he managed to retain an air of fastidious elegance. The bow and quiver across his back, the sword and dirk at his side, somehow looked purely ornamental when he wore them.
Anse looked up from his last victim and saw that the confusion no longer snarled around him. The street was heaped with dead and wounded, and a few individual battles were still going on. But the surviving guardsmen were in full flight, and the victorious warriors were shouting their triumph. 2b1af7f3a8